Brain Photobiomodulation Machine:
The Brain Photobiomodulation Machine is a therapeutic instrument based on the principle of photobiomodulation. It has a good therapeutic effect on traumatic events (stroke, traumatic brain injury, and global ischemia), degenerative diseases (dementia, Alzheimer's and Parkinson's), and psychiatric disorders (depression, anxiety, post traumatic stress disorder).
What is Photobiomodulation?
Photobiomodulation(PBM) therapy is defined as the utilization of non-ionizing electromagnetic energy to trigger photochemical changes within cellular structures that are receptive to photons. Mitochondria is particularly receptive to this process. At the cellular level, visible red and near infrared light (NIR) energy are absorbed by mitochondria, which perform the function of producing cellular energy called "ATP". The key to this entire process is a mitochondrial enzyme called cytochrome oxidase c, a chromophore, which accepts photonic energy of specific wavelengths when functioning below par.
Principle of Brain Photobiomodulation Machine:
Cytochrome C oxidase (CCO, also known as complex IV) is a specific structure in mitochondria that ACTS as a photon receptor and thus plays the PBM effect.PBM prevents respiratory inhibition (and correspondingly reduces energy storage) in stress cells by isolating nitric oxide (NO) and reversing the shift of oxygen in cytochrome C oxidase.This triggers transcription factors that alter gene expression levels.The binding of nitric oxide (NO) to copper (or heme) centers in the mitochondrial cytochrome C oxidase (CCO) inhibits cell respiration.But cytochrome C oxidase, which absorbs red or near-infrared (NIR) light, dissociates nitric oxide, restoring oxygen, increasing cellular respiration, and forming adenosine triphosphate (ATP).This triggers a cascade of intracellular reactions involving nitric oxide, reactive oxygen species (ROS), and cyclic adenosine phosphate (cAMP) that produce beneficial effects of PBM.
Specifications of Brain Photobiomodulation Machine:
|Name||Brain Photobiomodulation Machine|
|LED Wavelength||810 nm|
|Power(total helmet)||15 W|
|Power(one LED)||60 mW|
Main Function of Brain Photobiomodulation Machine:
• NIR light can penetrate the head and reach the brain.
• NIR is absorbed by cytochrome c oxidase in mitochondria.
• Heat-gated ion channels also play a role.
• Increased blood flow, energy, neuroprotection, less inflammation, brain repair.
• Can treat traumatic (stroke, TBI), neurodegenerative and psychiatric diseases.
Indicationsof Brain Photobiomodulation Machine:
1. Traumatic events (stroke, traumatic brain injury, and global ischemia).
2. Degenerative diseases (dementia, Alzheimer's and Parkinson's).
3. Psychiatric disorders (depression, anxiety, post traumatic stress disorder).
Feature of Brain Photobiomodulation Machine:
6-30 minutes time ajustable
1-20000Hz frequency adjustable
Suggest Different Frequencies for Different kinds of Diseases of Brain Photobiomodulation Machine:
|Disease||Treatment Time||Treatment Frequency|
|Cerebral arteriosclerosis Insufficient, blood supply to the brain||30 minutes||50 Hz|
|Brain atrophy||30 minutes||40-50 Hz|
|Alzheimer's disease (AD)||30 minutes||50 Hz|
|Children with autism||30 minutes||10-30 Hz|
|Cerebral thrombosis, Cerebral infarction||30 minutes||50 Hz|
|Lacunar infarction||30 minutes||50 Hz|
|Recovery of traumatic brain injury after operation||30 minutes||30 Hz|
|The recovery period after cerebral poisoning||30 minutes||30-50 Hz|
|Children with cerebral palsy||20-30 minutes||5-15 Hz|
|Parkinson's disease||30 minutes||30-50 Hz|
|Depression||20-30 minutes||50 Hz|
|Mental disorders||20-30 minutes||30-50 Hz|
|Insomnia||20-30 minutes||5-15 Hz|
|Nervous headache||20-30 minutes||20-40 Hz|
|High blood pressure||20-30 minutes||5-15 Hz|
|Brain fatigue disease||20-30 minutes||30 Hz|
|Memory loss||20-30 minutes||30 Hz|
|Neurasthenia||20-30 minutes||5-20 Hz|
|Schizophrenia||20-30 minutes||5-20 Hz|
How often does a person use the helmet?
For long-term chronic diseases, such as degenerative diseases, the recommended course of treatment is 3-6 months.
For short-term symptoms, such as concussion, migraine, depression, etc., the recommended course of treatment is 1-3 months.
According to the severity of the patient's symptoms, use 4-6 times a week, 1-2 times a day. At the beginning of the treatment, it is recommended to give the patient a process of adaptation. About the power intensity and time, you can start from 25% , 12 minutes. Gradually increase the power intensity and time step by step. After a adapation period, can use 75-100% intensity for 24-30 minutes.
Q&A of Brain Photobiomodulation Machine:
1. How long to set the timer?
You can choose 6 minutes - 12 minutes - 18 minutes - 24 minutes - 30 minutes
2. Are your infrared LEDs near infrared?
Our model is near infrared with 810nm.
3. Why do you use a mix of red LED and infrared LED? Why are they red?
We use 256pcs near infrared light for therapy. There are 4 pcs red led for instruction, to show you the device is working. Sometimes the near infrared is hardly to be seen from eyes, so the red light just for instruction, not for therapy function.
4. Have you found that your machine is able to actually penetrate the brain?
Yes, we have got a lot of research to prove this thoery which 810nm light can penetrate the brian.
5. How deep have you seen your machines tested to penetrate through the brain?
The 810nm light can penetrate our skull and works on nerve cell, and there is Cytochrome C Oxidase inside the Mitochondria of the cell, to promote the cell viability.
6. What frequency?
For the button model, the frequency is 40Hz, for the touch screen model, the frequency is 1-20,000 Hz adjustable.